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<p class="MsoNormal" style="margin:0cm 0cm 8pt;line-height:107%;font-size:11pt;font-family:Calibri"><b><span lang="DE"><span></span></span></b></p>
<p class="MsoNormal" style="margin:0cm 0cm 8pt;line-height:107%;font-size:11pt;font-family:Calibri"><span lang="DE">While official speeches emphasize
international solidarity in containing the corona pandemic, many countries are
focusing on national solutions for vaccine research.<span></span></span></p>
<p class="MsoNormal" style="margin:0cm 0cm 8pt;line-height:107%;font-size:11pt;font-family:Calibri"><span lang="DE">From Andreas Wulf (Medico Intl and PHM)<span></span></span></p>
<p class="MsoNormal" style="margin:0cm 0cm 8pt;line-height:107%;font-size:11pt;font-family:Calibri"><span lang="DE">The Russian government is playing at full
risk. The first nationally approved vaccine Sputnik 5 against the Corona virus
has immediately attracted strong international criticism, as no transparent
data have been made public and the relevant phase 3 studies have only just
begun<a style="color:rgb(5,99,193);text-decoration:underline" href="#_ftn1" name="_ftnref1" title=""><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span style="font-size:11pt;line-height:107%;font-family:Calibri" lang="DE">[1]</span></span></span></span></a>.
Nobody knows whether this "Sputnik moment" for Putin will not turn
into a "Challenger Disaster" if the vaccine turns out to be less
effective or has even dangerous side effects. But at the same time countries
are already queuing up to test and use this vaccine, the Philippine President
Duterte wants to be the first to test it and if it works for him, it will be
good for the whole country<a style="color:rgb(5,99,193);text-decoration:underline" href="#_ftn2" name="_ftnref2" title=""><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span style="font-size:11pt;line-height:107%;font-family:Calibri" lang="DE">[2]</span></span></span></span></a>.
<span></span></span></p>
<p class="MsoNormal" style="margin:0cm 0cm 8pt;line-height:107%;font-size:11pt;font-family:Calibri"><span lang="DE">This development of a vaccine nationalism can
be seen as a counterpoint to the brief 'spring of solidarity' when, on 4 May,
the WHO and the European Commission called with great fanfare for joint global
fundraising for the fight against the coronavirus. An impressive 15.9 billion
euros were raised until today, almost half of which was contributed by
"Team Europe" - the European Commission, the EU member states and the
European Investment Bank<a style="color:rgb(5,99,193);text-decoration:underline" href="#_ftn3" name="_ftnref3" title=""><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span style="font-size:11pt;line-height:107%;font-family:Calibri" lang="DE">[3]</span></span></span></span></a>.
The event was also memorable because Emmanuel Macron and Angela Merkel
designated a coronavirus vaccine as a "global public good". And EU
Commission President Ursula von der Leyen stressed that "governments and
global health organisations are pulling together in the fight against the
coronavirus".<span></span></span></p>
<p class="MsoNormal" style="margin:0cm 0cm 8pt;line-height:107%;font-size:11pt;font-family:Calibri"><span lang="DE"><span> </span></span></p>
<p class="MsoNormal" style="margin:0cm 0cm 8pt;line-height:107%;font-size:11pt;font-family:Calibri"><b><span lang="DE">International
solidarity?<span></span></span></b></p>
<p class="MsoNormal" style="margin:0cm 0cm 8pt;line-height:107%;font-size:11pt;font-family:Calibri"><span lang="DE">It sounded as if solidarity was written in
capital letters. Already in April, the WHO presented its "Access to
COVID-19 Tools (ACT) Accelerator"<a style="color:rgb(5,99,193);text-decoration:underline" href="#_ftn4" name="_ftnref4" title=""><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span style="font-size:11pt;line-height:107%;font-family:Calibri" lang="DE">[4]</span></span></span></span></a>,
an ambitious structure with the most important global health partnerships, in
which the development of vaccines, drugs and diagnostics as well as their
procurement and distribution were to be accelerated and coordinated. This
should also help prevent a deja-vu of the experience with the H1N1 influenza
pandemic in 2009: There should not be a repeat of the race for access to the
vaccine, with the rich countries winning out while the poorer countries are
supplied with "humanitarian crumbles" by the WHO.<span></span></span></p>
<p class="MsoNormal" style="margin:0cm 0cm 8pt;line-height:107%;font-size:11pt;font-family:Calibri"><span lang="DE">The U.S. government left this seemingly global
alliance early on by publicly launching a national ambitious vaccine program
for local pharmaceutical companies. Operation Warp Speed, which is worth ten billion
US dollars, is to develop and produce hundreds of millions of vaccine doses by
January 2021 at the latest, primarily for its own use, but also for the rest of
the world. But the USA is not the only country that is distancing itself from
the ACT Accelerator. Neither the Russian government with its Sputnik 5 nor the
Chinese government, which also promise an early success of their own vaccine
developments<a style="color:rgb(5,99,193);text-decoration:underline" href="#_ftn5" name="_ftnref5" title=""><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span style="font-size:11pt;line-height:107%;font-family:Calibri" lang="DE">[5]</span></span></span></span></a>, have
joined the WHO's Accelerator Initiative so far. India is also holding back,
which is all the more momentous because Indian vaccine production is currently
the most important in the Global South.<span></span></span></p>
<p class="MsoNormal" style="margin:0cm 0cm 8pt;line-height:107%;font-size:11pt;font-family:Calibri"><span lang="DE"><span> </span></span></p>
<p class="MsoNormal" style="margin:0cm 0cm 8pt;line-height:107%;font-size:11pt;font-family:Calibri"><b><span lang="DE">Who is
closest to himself<span></span></span></b></p>
<p class="MsoNormal" style="margin:0cm 0cm 8pt;line-height:107%;font-size:11pt;font-family:Calibri"><span lang="DE">So the full-bodied invocation of global
solidarity lasted only briefly. And with every further announcement of a
promising vaccine candidate, the façade continues to crumble. For it is
becoming increasingly clear that global production capacities are also limited
and may not be able to be increased as quickly. This is exactly what the WHO
initiative wants to prevent. Not only the US government, also the
"Inclusive Vaccine Alliance of Germany, France, Italy and the
Netherlands", for example, has made its own deals with pharmaceutical
companies for purchase guarantees and delivery quantities for successful
vaccine candidates. The EU Commission has taken over the current negotiations
with Sanofi-GSK<a style="color:rgb(5,99,193);text-decoration:underline" href="#_ftn6" name="_ftnref6" title=""><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span style="font-size:11pt;line-height:107%;font-family:Calibri" lang="DE">[6]</span></span></span></span></a>.
Politicians like von der Leyen like to use phrases like "nobody is safe
until everyone is safe". But when it comes to getting out of the social
and economic crisis as quickly as possible, their own citizens are still a
little closer than the world community.<span></span></span></p>
<p class="MsoNormal" style="margin:0cm 0cm 8pt;line-height:107%;font-size:11pt;font-family:Calibri"><span lang="DE">And so the COVAX Facility, the vaccine pillar
within the ACT Accelerator, which is organized by the WHO together with the
Global Alliance for Vaccines and Immunisation (GAVI) and the Coalition for
Epidemic Preparedness Innovations (CEPI), is making little progress towards a
global "buying and distribution pooling mechanism" for effective
Covid19 vaccines. COVAX is currently focusing on a portfolio of nine vaccine
candidates from different vaccine classes (DNA/mRNA; viral vectors, proteins).
Through agreements with research institutions and companies that will produce
the vaccines in the USA, Europe, China and Australia, the risk of having backed
the wrong horse in the end is to be minimized. In addition, this multinational
cooperation is intended to ensure that a promising product is ultimately
cheaper than if individual countries negotiate with manufacturers alone. The
experience of the Global Fund in the pooled procurement of AIDS / TB /Malaria
drugs is the inspiration here. <span></span></span></p>
<p class="MsoNormal" style="margin:0cm 0cm 8pt;line-height:107%;font-size:11pt;font-family:Calibri"><span lang="DE">As a sign of global solidarity in the Covid19
crisis, the COVAX Facility aims to support the financially weakest countries
with funds from global and national development budgets in the procurement of
the vaccine. So far, however, no financial commitments have been made. And
among the 75 countries that have at least signalled a possible participation in
the budgets, most of the financially strong countries with their own vaccine
production capacities are missing - in Europe, for example, the heavyweights
France, Italy, Great Britain and Germany<a style="color:rgb(5,99,193);text-decoration:underline" href="#_ftn7" name="_ftnref7" title=""><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span style="font-size:11pt;line-height:107%;font-family:Calibri" lang="DE">[7]</span></span></span></span></a>
.<span></span></span></p>
<p class="MsoNormal" style="margin:0cm 0cm 8pt;line-height:107%;font-size:11pt;font-family:Calibri"><span lang="DE"><span> </span></span></p>
<p class="MsoNormal" style="margin:0cm 0cm 8pt;line-height:107%;font-size:11pt;font-family:Calibri"><b><span lang="DE">Priority
supply<span></span></span></b></p>
<p class="MsoNormal" style="margin:0cm 0cm 8pt;line-height:107%;font-size:11pt;font-family:Calibri"><span lang="DE">But even in the COVAX Facility, not all
countries would be equal. The plan for the global distribution of a vaccine
envisages, as a first step, the simultaneous supply for 3% of the population in
every country, which should mainly include "indispensable key
persons", i.e. health, nursing and other professionals, in a first step...
Subsequently, in further tranches, 20 percent of the respective populations are
to be provided with the vaccine, with particular attention being paid to risk
groups such as the elderly and the chronically ill. However, "self-paying
countries" are already granted priority supply in this second procurement
round, while countries dependent on aid funds must wait until corresponding
quantities can be produced and paid for. On the way to a population-wide
supply, the differences in availability are widening more and more.<span></span></span></p>
<p class="MsoNormal" style="margin:0cm 0cm 8pt;line-height:107%;font-size:11pt;font-family:Calibri"><span lang="DE">It is also unclear whether GAVI actually has
the authority to negotiate successfully with the pharmaceutical companies.
There has been and still is great criticism of the fact that the manufacturers
are also represented with a seat and vote on the GAVI board. Experience from
the price and supply negotiations for the pneumococcal vaccines - GAVI's
flagship project - raises doubts: even after years, there is no real price
competition between the few manufacturers; the profits are enormous<a style="color:rgb(5,99,193);text-decoration:underline" href="#_ftn8" name="_ftnref8" title=""><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span style="font-size:11pt;line-height:107%;font-family:Calibri" lang="DE">[8]</span></span></span></span></a>.<span></span></span></p>
<p class="MsoNormal" style="margin:0cm 0cm 8pt;line-height:107%;font-size:11pt;font-family:Calibri"><span lang="DE"><span> </span></span></p>
<p class="MsoNormal" style="margin:0cm 0cm 8pt;line-height:107%;font-size:11pt;font-family:Calibri"><b><span lang="DE">Selfishness
also harms the rich countries<span></span></span></b></p>
<p class="MsoNormal" style="margin:0cm 0cm 8pt;line-height:107%;font-size:11pt;font-family:Calibri"><span lang="DE">Sothe <span> </span>COVAX Facility is anyway only a model of
"Solidarity light". But even for this one, six months after the
beginning of the pandemic, there is no sufficient global support. Instead,
competition and mutual accusations are intensifying. US and British governments
are accusing Russia and China of stealing vaccine data. It may be convenient
for the European states to point the finger at the US president and his
"America first" policy. However, they do not want to be reminded that
they are not honouring their own commitments. It is to be expected that the
selfish impulses in the fight against the pandemic will hinder the longer-term
strategy also for the technologically advanced states. This is because the production
and supply chains have long since been globalized, even in vaccine production -
even states such as the USA are dependent on secure trade and supply contracts.
And even if a country could protect itself, it remains dependent on the world
with its sales markets and suppliers. If there were an "Island of the
Blessed", it would also suffer from a prolonged global recession and a
continuing pandemic<a style="color:rgb(5,99,193);text-decoration:underline" href="#_ftn9" name="_ftnref9" title=""><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span style="font-size:11pt;line-height:107%;font-family:Calibri" lang="DE">[9]</span></span></span></span></a>.<span></span></span></p>
<p class="MsoNormal" style="margin:0cm 0cm 8pt;line-height:107%;font-size:11pt;font-family:Calibri"><span lang="DE">At the beginning of August, WHO
Director-General Dr. Tedros emphasized once again that in all probability there
would be no "silver bullet", i.e. a vaccine that is one hundred
percent effective in all people<a style="color:rgb(5,99,193);text-decoration:underline" href="#_ftn10" name="_ftnref10" title=""><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span style="font-size:11pt;line-height:107%;font-family:Calibri" lang="DE">[10]</span></span></span></span></a>.
This is one of the reasons why it would be in the "enlightened
self-interest" of all players to consistently rely on cooperation. The
fact that the German government is not involved in either the COVAX initiative
or the Covid19 Technology Patent Pool for the global benefit of health
knowledge shows how questionable the role of a self-proclaimed "Global
Health Champion" is.<span></span></span></p>
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<p class="gmail-MsoFootnoteText" style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:Calibri"><a style="color:rgb(5,99,193);text-decoration:underline" href="#_ftnref1" name="_ftn1" title=""><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span lang="DE"><span><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span style="font-size:10pt;line-height:107%;font-family:Calibri" lang="DE">[1]</span></span></span></span></span></a><span lang="DE"> <a href="https://www.themoscowtimes.com/2020/08/12/russias-covid-19-vaccine-breaches-crucial-scientific-and-ethical-international-standards-a71121" style="color:rgb(5,99,193);text-decoration:underline">https://www.themoscowtimes.com/2020/08/12/russias-covid-19-vaccine-breaches-crucial-scientific-and-ethical-international-standards-a71121</a><span></span></span></p>
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<div id="gmail-ftn2">
<p class="gmail-MsoFootnoteText" style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:Calibri"><a style="color:rgb(5,99,193);text-decoration:underline" href="#_ftnref2" name="_ftn2" title=""><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span lang="DE"><span><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span style="font-size:10pt;line-height:107%;font-family:Calibri" lang="DE">[2]</span></span></span></span></span></a><span lang="DE"><span> </span><a href="https://www.dw.com/en/philippines-duterte-volunteers-to-be-putins-coronavirus-vaccine-guinea-pig/a-54523030" style="color:rgb(5,99,193);text-decoration:underline">https://www.dw.com/en/philippines-duterte-volunteers-to-be-putins-coronavirus-vaccine-guinea-pig/a-54523030</a><span></span></span></p>
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<div id="gmail-ftn3">
<p class="gmail-MsoFootnoteText" style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:Calibri"><a style="color:rgb(5,99,193);text-decoration:underline" href="#_ftnref3" name="_ftn3" title=""><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span lang="DE"><span><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span style="font-size:10pt;line-height:107%;font-family:Calibri" lang="DE">[3]</span></span></span></span></span></a><span lang="DE"> <a href="https://global-response.europa.eu/index_de" style="color:rgb(5,99,193);text-decoration:underline">https://global-response.europa.eu/index_de</a><span></span></span></p>
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<p class="gmail-MsoFootnoteText" style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:Calibri"><a style="color:rgb(5,99,193);text-decoration:underline" href="#_ftnref4" name="_ftn4" title=""><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span lang="DE"><span><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span style="font-size:10pt;line-height:107%;font-family:Calibri" lang="DE">[4]</span></span></span></span></span></a><span lang="DE"><span> </span><a href="https://www.who.int/initiatives/act-accelerator" style="color:rgb(5,99,193);text-decoration:underline">https://www.who.int/initiatives/act-accelerator</a><span></span></span></p>
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<div id="gmail-ftn5">
<p class="gmail-MsoFootnoteText" style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:Calibri"><a style="color:rgb(5,99,193);text-decoration:underline" href="#_ftnref5" name="_ftn5" title=""><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span lang="DE"><span><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span style="font-size:10pt;line-height:107%;font-family:Calibri" lang="DE">[5]</span></span></span></span></span></a><span lang="DE"> <a href="https://www.nytimes.com/2020/08/02/world/europe/russia-trials-vaccine-October.html" style="color:rgb(5,99,193);text-decoration:underline">https://www.nytimes.com/2020/08/02/world/europe/russia-trials-vaccine-October.html</a><span class="gmail-MsoHyperlink" style="color:rgb(5,99,193);text-decoration:underline"> ; </span><a href="https://www.nature.com/articles/d41586-020-02244-1" style="color:rgb(5,99,193);text-decoration:underline">https://www.nature.com/articles/d41586-020-02244-1</a><span></span></span></p>
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<p class="gmail-MsoFootnoteText" style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:Calibri"><a style="color:rgb(5,99,193);text-decoration:underline" href="#_ftnref6" name="_ftn6" title=""><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span lang="DE"><span><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span style="font-size:10pt;line-height:107%;font-family:Calibri" lang="DE">[6]</span></span></span></span></span></a><span lang="DE"> <a href="https://ec.europa.eu/commission/presscorner/detail/en/ip_20_1439" style="color:rgb(5,99,193);text-decoration:underline">https://ec.europa.eu/commission/presscorner/detail/en/ip_20_1439</a><span></span></span></p>
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<p class="gmail-MsoFootnoteText" style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:Calibri"><a style="color:rgb(5,99,193);text-decoration:underline" href="#_ftnref7" name="_ftn7" title=""><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span lang="DE"><span><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span style="font-size:10pt;line-height:107%;font-family:Calibri" lang="DE">[7]</span></span></span></span></span></a><span lang="DE"> <a href="https://www.who.int/news-room/detail/15-07-2020-more-than-150-countries-engaged-in-covid-19-vaccine-global-access-facility" style="color:rgb(5,99,193);text-decoration:underline">https://www.who.int/news-room/detail/15-07-2020-more-than-150-countries-engaged-in-covid-19-vaccine-global-access-facility</a><span></span></span></p>
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<p class="gmail-MsoFootnoteText" style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:Calibri"><a style="color:rgb(5,99,193);text-decoration:underline" href="#_ftnref8" name="_ftn8" title=""><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span lang="DE"><span><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span style="font-size:10pt;line-height:107%;font-family:Calibri" lang="DE">[8]</span></span></span></span></span></a><span lang="DE"> <a href="https://msfaccess.org/analysis-and-critique-advance-market-commitment-amc-pneumococcal-conjugate-vaccines" style="color:rgb(5,99,193);text-decoration:underline">https://msfaccess.org/analysis-and-critique-advance-market-commitment-amc-pneumococcal-conjugate-vaccines</a><span></span></span></p>
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<p class="gmail-MsoFootnoteText" style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:Calibri"><a style="color:rgb(5,99,193);text-decoration:underline" href="#_ftnref9" name="_ftn9" title=""><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span lang="DE"><span><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span style="font-size:10pt;line-height:107%;font-family:Calibri" lang="DE">[9]</span></span></span></span></span></a><span lang="DE"> <a href="https://www.foreignaffairs.com/articles/united-states/2020-07-27/vaccine-nationalism-pandemic" style="color:rgb(5,99,193);text-decoration:underline">https://www.foreignaffairs.com/articles/united-states/2020-07-27/vaccine-nationalism-pandemic</a><span></span></span></p>
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<p class="gmail-MsoFootnoteText" style="margin:0cm 0cm 0.0001pt;font-size:10pt;font-family:Calibri"><a style="color:rgb(5,99,193);text-decoration:underline" href="#_ftnref10" name="_ftn10" title=""><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span lang="DE"><span><span class="gmail-MsoFootnoteReference" style="vertical-align:super"><span style="font-size:10pt;line-height:107%;font-family:Calibri" lang="DE">[10]</span></span></span></span></span></a><span lang="DE"> <a href="https://www.who.int/dg/speeches/detail/who-director-general-s-opening-remarks-at-the-media-briefing-on-covid-19---3-august-2020" style="color:rgb(5,99,193);text-decoration:underline">https://www.who.int/dg/speeches/detail/who-director-general-s-opening-remarks-at-the-media-briefing-on-covid-19---3-august-2020</a><span></span></span></p>
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