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<div><span class="gmail_quote">From: <b class="gmail_sendername">Ruggiero, Mrs. Ana Lucia (WDC)</b> <<a href="mailto:ruglucia@paho.org">ruglucia@paho.org</a>><br>crossposted from: <a href="mailto:EQUIDAD@listserv.paho.org">EQUIDAD@listserv.paho.org</a><br>
<br></span><b><font face="Arial" color="maroon" size="2"><span style="FONT-WEIGHT: bold; FONT-SIZE: 10pt; COLOR: maroon; FONT-FAMILY: Arial">Health Partnerships Review: Foc</span></font></b><b><font face="Arial" color="maroon" size="2"><span style="FONT-WEIGHT: bold; FONT-SIZE: 10pt; COLOR: maroon; FONT-FAMILY: Arial">using collaborative efforts on research and innovation for the health of the poor. </span></font></b><b><font face="Arial" color="navy" size="2"><span style="FONT-WEIGHT: bold; FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial"> </span></font></b><b><font face="Arial" color="navy" size="2"><span style="FONT-WEIGHT: bold; FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial">Global Forum for Health Research 2008</span></font></b></div>
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<p style="MARGIN-LEFT: 0.5in"><b><font face="Arial" color="navy" size="2"><span style="FONT-WEIGHT: bold; FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial"> </span></font></b><font face="Arial" color="navy" size="1"><span style="FONT-SIZE: 9pt; COLOR: navy; FONT-FAMILY: Arial">Available online as PDF file [102p.] at: <a onclick="return top.js.OpenExtLink(window,event,this)" href="http://www.globalforumhealth.org/filesupld/hpr/HealthPartnershipsReview_Full.pdf" target="_blank"><font color="navy"><span style="COLOR: navy">http://www.globalforumhealth.org/filesupld/hpr/HealthPartnershipsReview_Full.pdf</span></font></a> </span></font></p>
<p style="MARGIN-LEFT: 0.5in"><font face="Arial" color="navy" size="2"><span style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial"> </span></font><font face="Arial" color="navy" size="2"><span style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial">"The poor die young. Data from every part of the world show that, whether comparing richer and poorer populations within or between countries, those that are least well off have shorter life expectancies and heavier burdens of disease than those that are relatively wealthy. While the highest attainable standard of health has been declared a human right, this health inequity reflects a collective neglect at national and global levels – neglect of diseases, of health systems and ultimately of people…."</span></font></p>
<p style="MARGIN-LEFT: 0.5in"><font face="Arial" color="navy" size="2"><span style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial">"….Three areas of failure can be highlighted that represent different dimensions of the problem – failures of science (where basic knowledge or tools are lacking), failures of the market (where economic incentives for the production of needed medicines are lacking), and public health failures (where systems and programmes to implement available interventions are lacking)…." </span></font><i><font face="Arial" color="navy" size="1"><span style="FONT-SIZE: 8pt; COLOR: navy; FONT-STYLE: italic; FONT-FAMILY: Arial">>From Stephen Matlin, Executive Director, Global Forum for Health Research</span></font></i><font face="Arial" color="navy" size="2"><span style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial"></span></font></p>
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<p style="MARGIN-LEFT: 0.5in"><font face="Arial" color="navy" size="2"><span style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial">"…..Over the last few years, partnerships between public and private sector organizations have become an increasingly common mechanism to address some of the diseases of the poor in developing countries.</span></font></p>
<p style="MARGIN-LEFT: 0.5in"><font face="Arial" color="navy" size="2"><span style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial">The ultimate goal of most of these partnerships is to improve and increase access to treatment, particularly for 'neglected diseases'. Many also express the goal of contributing to the alleviation of poverty through improved health.</span></font></p>
<p style="MARGIN-LEFT: 0.5in"><font face="Arial" color="navy" size="2"><span style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial">The need for such partnerships can be explained by a failure of public health systems – the inability of the public sector to provide public goods entirely on its own, due to lack of resources; competing priorities for the limited resources available; management issues; conflict and post-conflict situations; etc. There is also a failure on the part of the private sector when there is little or no commercial incentive for the development of diagnostics and medicines for most of the diseases endemic in developing countries and affecting mainly the very poor…"</span></font></p>
<p style="MARGIN-LEFT: 0.5in"><font face="Arial" color="navy" size="2"><span style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial"></span></font></p>
<p style="MARGIN-LEFT: 0.5in"><font face="Arial" color="navy" size="2"><span style="FONT-WEIGHT: bold; FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial"><em><font size="1">Does anybody care to comment on this foreword? Claudio </font> </em></span></font></p>
<p style="MARGIN-LEFT: 0.5in"><b><font face="Arial" color="navy" size="2"><span style="FONT-WEIGHT: bold; FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial">Contents</span></font></b></p>
<p style="MARGIN-LEFT: 0.5in"><font face="Arial" color="navy" size="2"><span style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial">Foreword Stephen Matlin</span></font></p>
<p style="MARGIN-LEFT: 0.5in"><b><font face="Arial" color="navy" size="2"><span style="FONT-WEIGHT: bold; FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial">Focusing collaborative efforts on research and innovation for the health of the poor</span></font></b></p>
<p style="MARGIN-LEFT: 0.5in"><font face="Arial" color="navy" size="2"><span style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial">The PDP approach</span></font></p>
<p style="MARGIN-LEFT: 0.5in"><b><font face="Arial" color="navy" size="2"><span style="FONT-WEIGHT: bold; FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial"><br>The new landscape of product development partnerships (PDPs)</span></font></b></p>
<p style="MARGIN-LEFT: 0.5in"><font face="Arial" color="navy" size="2"><span style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial">Stefanie Meredith and Elizabeth Ziemba</span></font></p>
<p style="MARGIN-LEFT: 0.5in"><b><font face="Arial" color="navy" size="2"><span style="FONT-WEIGHT: bold; FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial"><br>Public–private partnerships in health systems - </span></font></b><font face="Arial" color="navy" size="2"><span style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial">Sania Nishtar</span></font></p>
<p style="MARGIN-LEFT: 0.5in"><b><font face="Arial" color="navy" size="2"><span style="FONT-WEIGHT: bold; FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial"> <br>Issues in assessing product development partnerships (PDPs) - </span></font></b><font face="Arial" color="navy" size="2"><span style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial">Lakshmi Sundaram</span></font></p>
<p style="MARGIN-LEFT: 0.5in"><b><font face="Arial" color="navy" size="2"><span style="FONT-WEIGHT: bold; FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial"> <br>Technological and social innovation: a unifying new paradigm for global health</span></font></b></p>
<p style="MARGIN-LEFT: 0.5in"><font face="Arial" color="navy" size="2"><span style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial">Charles A Gardner, Tara Acharya and Derek Yach</span></font></p>
<p style="MARGIN-LEFT: 0.5in"><b><font face="Arial" color="navy" size="2"><span style="FONT-WEIGHT: bold; FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial"> <br>Product development partnerships: public–private partnerships among unequal partners?</span></font></b></p>
<p style="MARGIN-LEFT: 0.5in"><font face="Arial" color="navy" size="2"><span style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial">Anna Wang</span></font></p>
<p style="MARGIN-LEFT: 0.5in"><font face="Arial" color="navy" size="2"><span style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial"> </span></font></p>
<p style="MARGIN-LEFT: 0.5in"><font face="Arial" color="navy" size="2"><span style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial"> <br></span></font><b><i><font face="Arial" color="maroon" size="2"><span style="FONT-WEIGHT: bold; FONT-SIZE: 10pt; COLOR: maroon; FONT-STYLE: italic; FONT-FAMILY: Arial">Research and development</span></font></i></b></p>
<p style="MARGIN-LEFT: 0.5in"><b><font face="Arial" color="navy" size="2"><span style="FONT-WEIGHT: bold; FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial">Facing the dual challenge of developing both products and research capacities for neglected diseases</span></font></b></p>
<p style="MARGIN-LEFT: 0.5in"><font face="Arial" color="navy" size="2"><span style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial">Piero L Olliaro and Stephen C Wayling</span></font></p>
<p style="MARGIN-LEFT: 0.5in"><b><font face="Arial" color="navy" size="2"><span style="FONT-WEIGHT: bold; FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial"> <br>The portfolio approach to successful product development in global health - </span></font></b><font face="Arial" color="navy" size="2"><span style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial">David Brown</span></font></p>
<p style="MARGIN-LEFT: 0.5in"><b><font face="Arial" color="navy" size="2"><span style="FONT-WEIGHT: bold; FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial"><br>The role of the health system in biotechnology in Brazil and Cuba - </span></font></b><font face="Arial" color="navy" size="2"><span style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial">Halla Thorsteinsdóttir</span></font></p>
<p style="MARGIN-LEFT: 0.5in"><b><font face="Arial" color="navy" size="2"><span style="FONT-WEIGHT: bold; FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial"><br>Sustainable (vaccine) development: the International AIDS Vaccine Initiative (IAVI) and capacity building</span></font></b></p>
<p style="MARGIN-LEFT: 0.5in"><font face="Arial" color="navy" size="2"><span style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial">Joanna Chataway and Rebecca Hanlin</span></font></p>
<p style="MARGIN-LEFT: 0.5in"><b><font face="Arial" color="navy" size="2"><span style="FONT-WEIGHT: bold; FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial"><br>Beyond market failures: IAVI and the organizational challenges of vaccine development</span></font></b></p>
<p style="MARGIN-LEFT: 0.5in"><font face="Arial" color="navy" size="2"><span lang="IT" style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial">Luigi Orsenigo, Stefano Brusoni and Eugenia Cacciatori </span></font></p>
<p style="MARGIN-LEFT: 0.5in"><font face="Arial" color="navy" size="2"><span style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial"> </span></font></p>
<p style="MARGIN-LEFT: 0.5in"><font face="Arial" color="navy" size="2"><span style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial"> <br></span></font><b><i><font face="Arial" color="maroon" size="2"><span style="FONT-WEIGHT: bold; FONT-SIZE: 10pt; COLOR: maroon; FONT-STYLE: italic; FONT-FAMILY: Arial">Clinical trials</span></font></i></b></p>
<p style="MARGIN-LEFT: 0.5in"><b><font face="Arial" color="navy" size="2"><span style="FONT-WEIGHT: bold; FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial">Clinical trial site capacity for malaria product development</span></font></b></p>
<p style="MARGIN-LEFT: 0.5in"><font face="Arial" color="navy" size="2"><span style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial">Mary Moran, Javier Guzman, Anne-Laure Ropars, Margaret Jorgensen, Sarah Potter, Alina McDonald and Hiwot Haile-Selassie</span></font></p>
<p style="MARGIN-LEFT: 0.5in"><b><font face="Arial" color="navy" size="2"><span style="FONT-WEIGHT: bold; FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial"><br>Issues surrounding the implementation of multiple product development partnership clinical trials in developing countries</span></font></b></p>
<p style="MARGIN-LEFT: 0.5in"><font face="Arial" color="navy" size="2"><span style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial">Gita Ramjee</span></font></p>
<p style="MARGIN-LEFT: 0.5in"><b><font face="Arial" color="navy" size="2"><span style="FONT-WEIGHT: bold; FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial"><br>Collaborative approach to clinical trials - </span></font></b><font face="Arial" color="navy" size="2"><span style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial">Charles S Mgone and Pascoal Mocumbi</span></font></p>
<p style="MARGIN-LEFT: 0.5in"><b><font face="Arial" color="navy" size="2"><span style="FONT-WEIGHT: bold; FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial"><br>Running clinical trials in partnership with communities - </span></font></b><font face="Arial" color="navy" size="2"><span style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial">Anjali Gopalan</span></font></p>
<p style="MARGIN-LEFT: 0.5in"><b><font face="Arial" color="navy" size="2"><span style="FONT-WEIGHT: bold; FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial"> </span></font></b></p>
<p style="MARGIN-LEFT: 0.5in"><b><i><font face="Arial" color="maroon" size="2"><span style="FONT-WEIGHT: bold; FONT-SIZE: 10pt; COLOR: maroon; FONT-STYLE: italic; FONT-FAMILY: Arial">Bringing products to market</span></font></i></b></p>
<p style="MARGIN-LEFT: 0.5in"><b><font face="Arial" color="navy" size="2"><span style="FONT-WEIGHT: bold; FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial">Getting diagnostics into countries - </span></font></b><font face="Arial" color="navy" size="2"><span style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial">Vinand M Nantulya</span></font></p>
<p style="MARGIN-LEFT: 0.5in"><b><font face="Arial" color="navy" size="2"><span style="FONT-WEIGHT: bold; FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial"><br>The control of neglected tropical diseases using access to available medicines through public–private partnerships</span></font></b></p>
<p style="MARGIN-LEFT: 0.5in"><font face="Arial" color="navy" size="2"><span style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial">Alan Fenwick, Peter J Hotez and David H Molyneux</span></font></p>
<p style="MARGIN-LEFT: 0.5in"><b><font face="Arial" color="navy" size="2"><span style="FONT-WEIGHT: bold; FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial"><br>The story of ASAQ: the first antimalarial product development partnership success</span></font></b></p>
<p style="MARGIN-LEFT: 0.5in"><font face="Arial" color="navy" size="2"><span style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial">Bernard Pécoul, Ann-Marie Sevcsik, John Amuasi, Graciela Diap and Jean-René Kiechel</span></font></p>
<p style="MARGIN-LEFT: 0.5in"><b><font face="Arial" color="navy" size="2"><span style="FONT-WEIGHT: bold; FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial"><br>Managing intellectual property for global health outcomes: the example of product development partnerships</span></font></b></p>
<p style="MARGIN-LEFT: 0.5in"><font face="Arial" color="navy" size="2"><span style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial">Robert Eiss</span></font></p>
<p style="MARGIN-LEFT: 0.5in"><b><font face="Arial" color="navy" size="2"><span style="FONT-WEIGHT: bold; FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial"><br>Regulatory strategies of product development partnerships: some perspectives</span></font></b></p>
<p style="MARGIN-LEFT: 0.5in"><font face="Arial" color="navy" size="2"><span style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial">Chris Hentschel, Jörg Möhrle and Jaya Banerji</span></font></p>
<p style="MARGIN-LEFT: 0.5in"><font face="Arial" color="navy" size="2"><span style="FONT-SIZE: 10pt; COLOR: navy; FONT-FAMILY: Arial"> </span></font></p></div></div>