PHA-Exchange> New Treatment for Severe Malaria
Claudio
claudio at hcmc.netnam.vn
Wed Oct 11 02:12:45 PDT 2006
From: "Leela McCullough" <leela at healthnet.org>
> http://www.medicalnewstoday.com/medicalnews.php?newsid=53132
>
> The most dangerous form of malaria is difficult to treat and claims two
> million lives a year. Now, researchers at Karolinska Institute in Sweden
> have developed a powerful new weapon against the disease.
>
> Severe anaemia, respiratory problems and encephalopathy are common and
> life-threatening consequences of serious malaria infection. The diseases
> are caused when P. falciparium infects the red blood cells, which then
> accumulate in large amounts, blocking the flow of blood in the capillaries
> of the brain and other organs.
>
> The reason that the blood cells conglomerate and lodge in the blood
> vessels is that once in the blood cell the parasite produces proteins that
> project from the surface of the cell and bind with receptors on other
> blood cells and on the vessel wall, and thus act like a glue. The
> challenge facing scientists has been to break these bonds so that the
> infected blood cells can be transported by the blood stream into the
> spleen and destroyed.
>
> Contact: Katarina Sternudd
> http://ki.se/ki/jsp/polopoly.jsp?d=138&l=en
> mailto:info at ki.se
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